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ISBN-10 :  0729542645

ISBN-13 ‏:‎ 978-0729542647

Author: Judy Craft; Christopher Gordon

Written by Judy Craft and Christopher Gordon, Understanding Pathophysiology 3e remains Australia and New Zealand’s leading pathophysiology text for nursing and allied health students. Updated to include the most current scientific and clinical case material across the life span, complex subject manner is presented in an approachable and easy-to-understand format. Beginning with essential concepts, the text examines the normal structure and function of each body system, followed by the alterations to that system caused by disease. Conditions particularly relevant to children and to the ageing are described in separate sections in each chapter to demonstrate disease processes across the life span.

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Table Of Content: 

  1. Cover image
  2. Title Page
  3. Table of Contents
  4. Copyright
  5. About the Authors
  6. Australian and New Zealand Contributors
  7. US Contributors
  8. Reviewers
  9. Preface
  10. Organisation of content
  11. The Australian and New Zealand context
  12. Concept maps: a unique feature of the text
  13. Acknowledgments
  14. Text Features
  15. Part One Essential concepts of pathophysiology
  16. Introduction
  17. Chapter 1 Introduction to clinical science
  18. Introduction
  19. Essential pathophysiology
  20. Essential anatomy
  21. Essential physiology
  22. Essential chemistry
  23. Essential physics
  24. Review questions
  25. Chapter 2 Homeostasis
  26. Introduction
  27. Homeostasis
  28. Regulation of homeostasis
  29. Disturbances of homeostasis lead to pathophysiology
  30. Review questions
  31. Chapter 3 Cellular structure and function
  32. Introduction
  33. Cellular structure and function
  34. Cellular components
  35. The cell membrane
  36. Cellular receptors and communication
  37. Membrane transport
  38. Cellular metabolism
  39. Tissues
  40. Review questions
  41. Chapter 4 Altered cellular function
  42. Introduction
  43. Causes of cellular injury
  44. Mechanisms of cellular injury
  45. Cellular adaptation
  46. Reversible and irreversible cell injury
  47. Death
  48. Review questions
  49. Chapter 5 Genes
  50. Introduction
  51. The nucleus
  52. Cell proliferation
  53. DNA, RNA and proteins: heredity at the molecular level
  54. Elements of genetics
  55. Inheritance of traits
  56. Newborn screening
  57. Review questions
  58. Part Two Alterations to regulation and control
  59. Introduction
  60. Chapter 6 The structure and function of the neurological system
  61. Introduction
  62. Organisation of the nervous system
  63. Cells of the nervous system
  64. Nerve injury and regeneration
  65. The nerve impulse
  66. The central nervous system
  67. The peripheral nervous system
  68. The autonomic nervous system
  69. Sensory function
  70. Review questions
  71. Chapter 7 Pain
  72. Introduction
  73. The definition of pain
  74. Types of pain
  75. Pain terminology
  76. The physiology of pain
  77. Clinical manifestations of pain
  78. Evaluation and treatment
  79. Pathophysiology of pain
  80. Review questions
  81. Chapter 8 Concepts of neurological dysfunction
  82. Introduction
  83. Alterations in cerebral homeostasis
  84. Alterations in cognitive function
  85. Alterations in motor function
  86. Review questions
  87. Chapter 9 Alterations of neurological function across the life span
  88. Introduction
  89. Cerebrovascular disorders
  90. Trauma to the central nervous system
  91. Degenerative disorders of the central nervous system
  92. Peripheral nervous system and neuromuscular junction disorders
  93. Infection and inflammation of the central nervous system
  94. Tumours of the nervous system
  95. Review questions
  96. Chapter 10 The structure and function of the endocrine system
  97. Introduction
  98. Mechanisms of hormonal regulation
  99. The structure and function of the endocrine glands
  100. Review questions
  101. Chapter 11 Alterations of endocrine function across the life span
  102. Introduction
  103. Mechanisms of hormonal alterations
  104. Alterations of pituitary function
  105. Alterations of adrenal function
  106. Alterations of pancreatic function
  107. Alterations of thyroid function
  108. Alterations of parathyroid function
  109. Review questions
  110. Part Three Alterations to protection and movement
  111. Introduction
  112. Chapter 12 The structure and function of the immune system
  113. Introduction
  114. Human defence mechanisms
  115. Humoral and cell-mediated immunity
  116. Induction of the immune response
  117. Review questions
  118. Chapter 13 Inflammation and fever
  119. Introduction
  120. Acute inflammation
  121. Cellular components of inflammation
  122. Inflammatory mediators
  123. Plasma protein systems
  124. Chronic inflammation
  125. Clinical manifestations of inflammation
  126. Fever
  127. Wound healing
  128. Review questions
  129. Chapter 14 Infection
  130. Introduction
  131. Infection rates
  132. Definitions
  133. Microorganisms
  134. Antimicrobials
  135. Vaccines
  136. Infections
  137. Antimicrobial resistance
  138. Review questions
  139. Chapter 15 Alterations of immune function across the life span
  140. Introduction
  141. Hypersensitivity reactions
  142. Transplantation
  143. The ABO blood group system
  144. Autoimmune diseases
  145. Immune deficiencies
  146. Review questions
  147. Chapter 16 The structure and function of the haematological system
  148. Introduction
  149. Components of the haematological system
  150. The development of blood cells
  151. The mechanisms of haemostasis
  152. Review questions
  153. Chapter 17 Alterations of haematological function across the life span
  154. Introduction
  155. Alterations of erythrocyte function
  156. Alterations of platelets and coagulation
  157. Alterations of leucocytes
  158. Alterations of lymphoid function
  159. Review questions
  160. Chapter 18 The structure and function of the integumentary system
  161. Introduction
  162. The structure of the skin
  163. Appendages of the skin
  164. The function of the integumentary system
  165. Review questions
  166. Chapter 19 Alterations of the integumentary system across the life span
  167. Introduction
  168. Skin lesions
  169. Skin cancer
  170. Inflammatory disorders of the skin
  171. Infections of the integumentary system
  172. Traumatic conditions of the integumentary system
  173. Vascular disorders
  174. Review questions
  175. Chapter 20 The structure and function of the musculoskeletal system
  176. Introduction
  177. The structure and function of bones
  178. The structure and function of joints
  179. The structure and function of skeletal muscles
  180. Review questions
  181. Chapter 21 Alterations of musculoskeletal function across the life span
  182. Introduction
  183. Musculoskeletal injuries
  184. Disorders of bone and joints
  185. Disorders of skeletal muscle
  186. Integrative conditions related to the musculoskeletal system
  187. Review questions
  188. Part Four Alterations to body maintenance
  189. Introduction
  190. Chapter 22 The structure and function of the cardiovascular and lymphatic systems
  191. Introduction
  192. The circulatory system
  193. The structure of the heart
  194. Blood flow during the cardiac cycle
  195. The coronary circulation
  196. Structures that control heart function
  197. The electrocardiogram
  198. Factors affecting cardiac performance
  199. The physiology of cardiovascular control
  200. The systemic circulation
  201. Blood pressure and blood flow
  202. The lymphatic system
  203. Review questions
  204. Chapter 23 Alterations of cardiovascular function across the life span
  205. Introduction
  206. Alterations of blood flow and pressure
  207. Alterations of the heart wall
  208. Alterations of cardiac conduction
  209. Heart failure
  210. Shock
  211. Review questions
  212. Chapter 24 The structure and function of the pulmonary system
  213. Introduction
  214. The structure of the pulmonary system
  215. The function of the pulmonary system
  216. Review questions
  217. Chapter 25 Alterations of pulmonary function across the life span
  218. Introduction
  219. Disorders of the pulmonary system
  220. Infections of the pulmonary system
  221. Lung cancer
  222. Obstructive sleep apnoea
  223. Alterations of pulmonary blood flow and pressure
  224. Clinical manifestations of pulmonary alterations
  225. Review questions
  226. Chapter 26 The structure and function of the digestive system
  227. Introduction
  228. An overview of the digestive system
  229. The mouth, pharynx and oesophagus
  230. The stomach
  231. The small intestine
  232. Accessory organs of digestion
  233. The large intestine
  234. An overview of nutrition
  235. Review questions
  236. Chapter 27 Alterations of digestive function across the life span
  237. Introduction
  238. Disorders of the gastrointestinal tract
  239. Clinical manifestations of gastrointestinal tract alterations
  240. Disorders of the hepatobiliary system and pancreas
  241. Review questions
  242. Chapter 28 The structure and function of the urinary system
  243. Introduction
  244. The structure of the kidneys
  245. The function of the kidneys
  246. Urine
  247. Urinary structures
  248. Micturition
  249. Review questions
  250. Chapter 29 Fluids and electrolytes, acids and bases
  251. Introduction
  252. Fluid balance
  253. Electrolyte balance
  254. Acid–base balance
  255. Review questions
  256. Chapter 30 Alterations of renal and urinary tract function across the life span
  257. Introduction
  258. Urinary tract obstruction
  259. Urinary tract infection
  260. Glomerular disorders
  261. Chronic kidney disease
  262. Acute kidney injury
  263. Tumours
  264. Review questions
  265. Part Five Alterations to continuity
  266. Introduction
  267. Chapter 31 The structure and function of the reproductive systems
  268. Introduction
  269. The structure and function of the male reproductive system
  270. The structure and function of the female reproductive system
  271. Puberty in males and females
  272. Gametogenesis
  273. Male and female sexual responses
  274. Conception, gestation and parturition
  275. Review questions
  276. Chapter 32 Alterations of the reproductive systems across the life span
  277. Introduction
  278. Classification of reproductive system alterations
  279. Cancer
  280. Disorders of the female reproductive system
  281. Disorders of the male reproductive system
  282. Disorders of the breast
  283. Fertility
  284. Assisted reproductive technologies
  285. Major sexually transmitted infections
  286. Review questions
  287. Part Six Contemporary health issues
  288. Introduction
  289. Chapter 33 Introduction to contemporary health issues
  290. Introduction
  291. Australia and New Zealand: demographics
  292. Chronic diseases
  293. Mental health
  294. Indigenous health
  295. Contemporary lifestyle
  296. Obesity
  297. Health promotion initiatives
  298. Review questions
  299. Chapter 34 Stress and chronic disease
  300. Introduction
  301. The general adaptation syndrome
  302. Stressors
  303. The detection of stress
  304. Physiological processes of the stress response
  305. Physiological effects of the stress response
  306. Benefits of the stress response
  307. Health alterations with chronic stress
  308. Modulation of the stress response
  309. Stress and sleep
  310. Review questions
  311. Chapter 35 Obesity
  312. Introduction
  313. The progression to overweight and obesity
  314. Evaluation of body size
  315. Obesity
  316. Metabolic syndrome
  317. Review questions
  318. Chapter 36 Type 2 diabetes
  319. Introduction
  320. Diabetes mellitus
  321. Understanding the relationship between obesity and diabetes
  322. Review questions
  323. Chapter 37 Cancer
  324. Introduction
  325. Cancer is a chronic disease
  326. Cancer characteristics and terminology
  327. The genetic basis of cancer
  328. Types of gene mutations in cancer
  329. Cancer, immunity, inflammation and infection
  330. Gene–environment interaction
  331. Diagnosis and evaluation of cancer
  332. Clinical manifestations of cancer and cancer treatments
  333. Cancer treatments
  334. Cancers of greatest significance in Australia and New Zealand
  335. The role of cancer screening
  336. Cancer across the life span
  337. Review questions
  338. Chapter 38 Genes, genetic diseases and the environment
  339. Introduction
  340. Studying genetic disease
  341. Genetic disorders
  342. Single gene disorders
  343. Multifactorial inheritance
  344. Conditions arising from genetic and environmental factors
  345. The relative importance of genetic and environmental contributions to disease
  346. The prevention of disease
  347. Genetic screening
  348. Review questions
  349. Chapter 39 Neurobiology of mental illness
  350. Introduction
  351. The epidemiology of mental illness in Australia and New Zealand
  352. Genetics and mental illness
  353. Neurotransmitters
  354. Classification systems
  355. Anxiety disorders
  356. Mood disorders
  357. Schizophrenia
  358. Substance use
  359. Eating disorders
  360. Personality disorders
  361. Review questions
  362. Chapter 40 Indigenous health issues in Australia
  363. Introduction
  364. The Indigenous Australian population
  365. Indigenous health
  366. Conditions affecting the wellbeing of Indigenous Australians
  367. Common threads — factors contributing to health problems
  368. Social determinants of Indigenous health
  369. Closing the Gap
  370. Review questions
  371. Chapter 41 Māori health in Aotearoa New Zealand
  372. Introduction
  373. The New Zealand Māori population
  374. Māori health
  375. Conditions affecting the wellbeing of Māori
  376. Factors contributing to health problems
  377. Social determinants of Māori health
  378. Review questions
  379. Appendix A Normal reference laboratory values
  380. Appendix B Prefixes, suffixes and root words commonly used in health sciences
  381. Glossary
  382. References
  383. Image and text credits

 

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