Test Bank for Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition

This is completed downloadable of Test Bank for Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition

Product Details:

• ISBN-10 ‏ : ‎ 9780323583473
• ISBN-13 ‏ : ‎ 978-0275972486
• Author:  Kathryn L. McCance

Learn the what, how, and why of pathophysiology! With easy-to-read, in-depthdescriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 8th Edition helps you understand the most important and most complex pathophysiology concepts. This updated text includes more than 1,300 full-color illustrations and photographs to make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW chapter on obesity and nutritional disorders, along withexpanded coverage of rare diseases and epigenetics. It’s the most comprehensive and authoritative pathophysiology text available!

• The most comprehensive and authoritative pathophysiology text on the market provides unparalleled coverage of Pathophysiology content.
• Over 1,300 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes ― more than in any other pathophysiology text.
• Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment.
• Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content.
• Outstanding authors Kathryn McCance and Sue Huether have extensive backgrounds as researchers and instructors, and utilize expert contributors, consultants, and reviewers in developing this edition.
• Algorithms and flowcharts of diseases and disorders make it easy for you to follow the sequential progression of disease processes.
• Additional What’s New boxes highlight the most current research and clinical development.
• Nutrition and Disease boxes explain the link between concepts of health promotion and disease.
• Chapter summary reviews provide concise synopses of the main points of each chapter.

• NEW! Chapter on obesity and nutritional disorders thoroughly covers these growing global concerns.
• NEW! Added coverage of rare diseases and epigenetics further explore genetic disease traits.
• NEW! Over 50 new or heavily revised illustrations visually highlight pathophysiology concepts.
• NEW! More than 30 new 3D animations on Evolve bring difficult concepts to life for a new perspective on disease processes.

Table of Content:

• Cover image
• Title Page
• Table of Contents
• What’s New?
• About the Cover Image
• Copyright
• Contributors
• Reviewers
• Preface
• Organization and Content: What’s New in the Eighth Edition
• Features to Promote Learning
• Art Program
• Ancillaries
• Acknowledgments
• Introduction to Pathophysiology
• References
• Part One Central Concepts of Pathophysiology: Cells and Tissues
• Unit I The Cell
• 1 Cellular Biology
• Prokaryotes and Eukaryotes
• Cellular Functions
• Structure and Function of Cellular Components
• Cell-to-Cell Adhesions
• Cellular Communication and Signal Transduction
• Cellular Metabolism
• Membrane Transport: Cellular Intake and Output
• Cellular Reproduction: the Cell Cycle
• Tissues
• Summary Review
• Key Terms
• References
• 2 Altered Cellular and Tissue Biology
• Cellular Adaptation
• Cellular Injury
• Manifestations of Cellular Injury
• Cellular Death
• Aging and Altered Cellular and Tissue Biology
• Somatic Death
• Summary Review
• Key Terms
• References
• 3 The Cellular Environment
• Distribution of Body Fluids
• Aging and Distribution of Body Fluids
• Alterations in Water Movement
• Sodium, Chloride, and Water Balance
• Alterations in Sodium, Water, and Chloride Balance
• Alterations in Potassium, Calcium, Phosphate, and Magnesium Balance
• Acid-Base Balance
• Summary Review
• Key Terms
• References
• Unit II Genes, Gene-Environment Interaction, and Epigenetics
• 4 Genes and Genetic Diseases
• DNA, RNA, and Proteins: Heredity at the Molecular Level
• Chromosomes
• Elements of Formal Genetics
• Transmission of Genetic Diseases
• Linkage Analysis and Gene Identification
• Summary Review
• Key Terms
• References
• 5 Genes, Environment-Lifestyle, and Common Diseases
• Factors Influencing Incidence of Disease in Populations
• Principles of Multifactorial Inheritance
• Nature and Nurture: Disentangling the Effects of Genes and Environment
• Genetics of Common Diseases
• Summary Review
• Key Terms
• References
• 6 Epigenetics and Disease
• Overview of Epigenetic Mechanisms
• Epigenetics and Human Development
• Genomic Imprinting
• Epigenetics in Cognitive Development and Mental Health
• Exploring the Possible Multigenerational Persistence of Epigenetic States That Arise in Response to Environmental Factors
• Epigenetic Change Over the Life Span
• Molecular and Computational Tools for Exploring Epigenetic States
• Epigenetics and Cancer
• Emerging Strategies for the Treatment of Epigenetic Disease
• Future Directions
• Summary Review
• Key Terms
• References
• Unit III Mechanisms of Self-Defense
• 7 Innate Immunity
• Human Defense Mechanisms
• First Line of Defense: Physical, Mechanical, and Biochemical Barriers and Normal Microbiome
• Second Line of Defense: Inflammation
• Local Manifestations of Inflammation
• Systemic Manifestations of Acute Inflammation
• Chronic Inflammation
• Wound Healing
• Pediatrics: Innate Immunity in the Newborn Child
• Aging: Innate Immunity in the Older Adult Population
• Summary Review
• Key Terms
• References
• 8 Adaptive Immunity
• General Characteristics of Adaptive Immunity
• Recognition and Response
• Generation of Clonal Diversity
• Induction of an Immune Response: Clonal Selection
• Effector Mechanisms
• Fetal and Neonatal Immune Function
• Aging and Immune Function
• Summary Review
• Key Terms
• References
• 9 Alterations in Immunity and Inflammation
• Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity
• References:
• Deficiencies in Immunity
• Summary Review
• Key Terms
• References
• 10 Infection
• Emerging Infections
• References
• Microorganisms and Humans: a Dynamic Relationship
• Microorganisms and Infections
• References
• References
• References
• References
• Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome
• Countermeasures Against Pathogens
• References
• Summary Review
• Key Terms
• References
• 11 Stress and Disease
• Historical Background and General Concepts
• Concepts of Stress, Homeostasis, and Allostasis
• Stress Response
• Stress, Illness, and Coping
• Aging and Stress: Stress-Age Syndrome
• Summary Review
• Key Terms
• References
• Unit IV Cellular Proliferation: Cancer
• 12 Cancer Biology
• Cancer Characteristics and Terminology
• The Biology of Cancer Cells
• Clinical Manifestations of Cancer
• Diagnosis and Staging of Cancer
• Treatment of Cancer
• Targeted Disruption of Cancer
• Summary Review
• Key Terms
• References
• 13 Cancer Epidemiology
• Genetics, Epigenetics, and Tissue
• Incidence and Mortality Trends
• In Utero and Early Life Conditions
• Environmental-Lifestyle Factors
• Chemicals and Occupational Hazards as Carcinogens
• Summary Review
• Key Terms
• References
• 14 Cancer in Children
• Incidence and Types of Cancer
• Etiology
• Prognosis
• Summary Review
• Key Terms
• References
• Part Two Pathophysiologic Alterations: Organs and Systems
• Unit V Pathophysiologic Alterations: Organs and Systems
• 15 Structure and Function of the Neurologic System
• Overview and Organization of the Nervous System
• Cells of the Nervous System
• Nerve Impulse
• Central Nervous System
• Peripheral Nervous System
• Autonomic Nervous System
• Aging and the Nervous System
• Tests of Nervous System Structure and Function
• Summary Review
• Key Terms
• References
• 16 Pain, Temperature Regulation, Sleep, and Sensory Function
• Pain
• Pediatrics and Perception of Pain
• Aging and Perception of Pain
• Temperature Regulation
• Pediatrics and Temperature Regulation
• Aging and Temperature Regulation
• Sleep
• Pediatrics and Sleep Patterns
• Aging and Sleep Patterns
• Somatosensory Function and the Special Senses
• Aging and Vision
• Aging and Hearing
• Aging and Olfaction and Taste
• Summary Review
• Key Terms
• References
• 17 Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
• Alterations in Cognitive Systems
• Alterations in Cerebral Hemodynamics
• Alterations in Neuromotor Function
• Summary Review
• Key Terms
• References
• 18 Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
• Central Nervous System Disorders
• Peripheral Nervous System and Neuromuscular Junction Disorders
• Tumors of the Central Nervous System
• Summary Review
• Key Terms
• References
• 19 Neurobiology of Schizophrenia, Mood Disorders, Anxiety Disorders, and Obsessive-Compulsive Disorder
• Schizophrenia
• Mood Disorders: Depression and Bipolar Disorder
• Anxiety Disorders
• Obsessive-Compulsive Disorder
• Summary Review
• Key Terms
• References
• 20 Alterations of Neurologic Function in Children
• Development of the Nervous System in Children
• Structural Malformations
• Alterations in Function: Encephalopathies
• Cerebrovascular Disease in Children
• Epilepsy and Seizure Disorders in Children
• Childhood Tumors
• Summary Review
• Key Terms
• References
• Unit VI The Endocrine System
• 21 Mechanisms of Hormonal Regulation
• Mechanisms of Hormonal Regulation
• Structure and Function of the Endocrine Glands
• Aging and the Endocrine System
• Summary Review
• Key Terms
• References
• 22 Alterations of Hormonal Regulation
• Mechanisms of Hormonal Alterations
• Alterations of the Hypothalamic-Pituitary System
• Alterations of Thyroid Function
• Alterations of Parathyroid Function
• Dysfunction of the Endocrine Pancreas: Diabetes Mellitus
• Alterations of Adrenal Function
• Summary Review
• Key Terms
• References
• 23 Obesity and Disorders of Nutrition
• Adipose Tissue
• Obesity
• Anorexia Nervosa, Bulimia Nervosa, and Binge Eating Disorder
• Starvation
• Anorexia of Aging
• Summary Review
• Key Terms
• References
• Unit VII The Reproductive Systems
• 24 Structure and Function of the Reproductive Systems
• Development of the Reproductive Systems
• The Female Reproductive System
• Structure and Function of the Breast
• The Male Reproductive System
• Tests of Reproductive Function
• Aging and Reproductive Function
• Summary Review
• Key Terms
• References
• 25 Alterations of the Female Reproductive System
• Abnormalities of Reproductive Tract Development
• Alterations of Sexual Maturation
• Disorders of the Female Reproductive System
• Disorders of the Female Breast
• Summary Review
• Key Terms
• References
• 26 Alterations of the Male Reproductive System
• Alterations of Sexual Maturation
• Disorders of the Male Reproductive System
• Disorders of the Male Breast
• Summary Review
• Key Terms
• References
• 27 Sexually Transmitted Infections
• Sexually Transmitted Urogenital Infections
• Sexually Transmitted Infections of Other Body Systems
• Summary Review
• Key Terms
• References
• Unit VIII The Hematologic System
• 28 Structure and Function of the Hematologic System
• Components of the Hematologic System
• Development of Blood Cells
• References
• Mechanisms of Hemostasis
• Clinical Evaluation of the Hematologic System
• Pediatrics and the Hematologic System
• Aging and the Hematologic System
• Summary Review
• Key Terms
• References
• 29 Alterations of Erythrocyte, Platelet, and Hemostatic Function
• Anemia
• Myeloproliferative Red Blood Cell Disorders
• Alterations of Platelets and Coagulation
• Summary Review
• Key Terms
• References
• 30 Alterations of Leukocyte and Lymphoid Function
• Alterations of Leukocyte Function
• Alterations of Lymphoid Function
• Alterations of Splenic Function
• Summary Review
• Key Terms
• References
• 31 Alterations of Hematologic Function in Children
• Fetal and Neonatal Hematopoiesis
• Postnatal Changes in the Blood
• Disorders of Erythrocytes
• Disorders of Coagulation and Platelets
• Neoplastic Disorders
• Summary Review
• Key Terms
• References
• Unit IX The Cardiovascular and Lymphatic Systems
• 32 Structure and Function of the Cardiovascular and Lymphatic Systems
• Circulatory System
• The Heart
• The Systemic Circulation
• Lymphatic System
• Tests of Cardiovascular Function
• Aging and the Cardiovascular System
• Summary Review
• Key Terms
• References
• 33 Alterations of Cardiovascular Function
• Diseases of the Veins
• Diseases of the Arteries
• Disorders of the Heart Wall
• Manifestations of Heart Disease
• Summary Review
• Key Terms
• References
• 34 Alterations of Cardiovascular Function in Children
• Development of The Cardiovascular System
• Congenital Heart Defects
• Acquired Cardiovascular Disorders
• Summary Review
• Key Terms
• References
• Unit X The Pulmonary System
• 35 Structure and Function of the Pulmonary System
• Structures of the Pulmonary System
• References
• Functions of the Pulmonary System
• Tests of Pulmonary Function
• Aging and the Pulmonary System
• Summary Review
• Key Terms
• References
• 36 Alterations of Pulmonary Function
• Clinical Manifestations of Pulmonary Alterations
• Disorders of the Chest Wall and Pleura
• Pulmonary Disorders
• References
• Summary Review
• Key Terms
• References
• 37 Alterations of Pulmonary Function in Children
• Structure and Function
• Disorders of the Upper Airways
• Disorders of the Lower Airways
• Sudden Infant Death Syndrome
• Summary Review
• Key Terms
• References
• Unit XI The Renal and Urologic Systems
• 38 Structure and Function of the Renal and Urologic Systems
• Structures of the Renal System
• Renal Blood Flow
• Kidney Function
• Tests of Renal Function
• Aging and Renal Function
• Summary Review
• Key Terms
• References
• 39 Alterations of Renal and Urinary Tract Function
• Urinary Tract Obstruction
• Urinary Tract Infection
• Glomerular Disorders
• Acute Kidney Injury
• Chronic Kidney Disease
• Summary Review
• Key Terms
• References
• 40 Alterations of Renal and Urinary Tract Function in Children
• Structure and Function of the Urinary System in Children
• Alterations in Renal and Bladder Function in Children
• Summary Review
• Key Terms
• References
• Unit XII The Digestive System
• 41 Structure and Function of the Digestive System
• The Gastrointestinal Tract
• Accessory Organs of Digestion
• Tests of Digestive Function
• Aging and the Gastrointestinal System
• Summary Review
• Key Terms
• References
• 42 Alterations of Digestive Function
• Disorders of the Gastrointestinal Tract
• Disorders of the Accessory Organs of Digestion
• Cancer of the Digestive System
• Summary Review
• Key Terms
• References
• 43 Alterations of Digestive Function in Children
• Disorders of the Gastrointestinal Tract
• Disorders of the Liver
• Summary Review
• Key Terms
• References
• Unit XIII The Musculoskeletal System
• 44 Structure and Function of the Musculoskeletal System
• Structure and Function of Bones
• Structure and Function of Joints
• Structure and Function of Skeletal Muscles
• Tests of Musculoskeletal Function
• Aging and the Musculoskeletal System
• Summary Review
• Key Terms
• References
• 45 Alterations of Musculoskeletal Function
• Musculoskeletal Injuries
• Disorders of Bones
• Disorders of Joints
• References
• Disorders of Skeletal Muscle
• Summary Review
• Key Terms
• References
• 46 Alterations of Musculoskeletal Function in Children
• Musculoskeletal Development in Children
• Musculoskeletal Alterations in Children
• Nonaccidental Trauma
• Summary Review
• Key Terms
• References
• Unit XIV The Integumentary System
• 47 Structure, Function, and Disorders of the Integument
• Structure and Function of the Skin
• Aging and Skin Integrity
• Disorders of the Skin
• Disorders of the Hair
• Disorders of the Nail
• Summary Review
• Key Terms
• References
• 48 Alterations of the Integument in Children
• Acne Vulgaris
• Dermatitis
• Infections of the Skin
• Insect Bites and Parasites
• Cutaneous Hemangiomas and Vascular Malformations
• Other Skin Disorders
• Summary Review
• Key Terms
• References
• Unit XV Multiple Interacting Systems
• 49 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
• Shock
• Multiple Organ Dysfunction Syndrome
• Burns
• Summary Review
• Key Terms
• References
• 50 Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children
• Shock and Multiple Organ Dysfunction Syndrome
• Burns
• Summary Review
• Key Terms
• References
• Glossary

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